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23 Apr, 2025
A new study led by Dr. Michael Wheeler at Mass General Brigham reveals that psychedelics like psilocybin and MDMA may reduce inflammation and reset brain-immune communication, helping to ease stress-related fear behaviors. In mouse models of chronic stress, researchers found that immune cells migrated to the brain and intensified fear responses- effects that psychedelics were able to prevent. Similar patterns were observed in human brain samples, suggesting potential for new treatments for conditions like depression and inflammatory disorders. Clinical trials are now underway to explore these findings further.